Amphetamines

Amphetamines be part of a class of drugs called stimulants that affect the total nervous system. It is also known as 1-methyl-2-phenethylamine, 1-phenyl-2-aminopropane, and Benzedrine. It is made up of a 50/50 mixture of the l and d isomers. The l isomer affects the body, and the d isomer affects the brain. It boils at 200ºC and is dissolvable in alcohol and ether, slightly soluble in water. It was postmortem examination created in Germany in 1887. In the 1930s and 40s amphetamine was office in the treatment of asthma, depression, obesity, and narcolepsy. Amphetamines chemical structure is very resembling to the neurotransmitter Adrenaline. chemic structure of Amphetamine, C H CH CH(NH ) CH Method of Preparation at that place are many ways of creating amphetamines. unity way is to dispense two mols, for example, 270 grams, of racemic amphetamine base to play off with iodine mol (150 grams) of d-tartaric hot, forming a dl-amphetamine d-tartrate, or a unbi ased salt. The achromatic salt obtained is dissolved by the addition of nearly 1 litre, of ethanol, and heating to boiling point. The solution then must(prenominal) be cooled to elbow room temperature with occasional stirring to effect crystallisation. The crystals are filtered out and result be found to contain laevo enantiomorph, which is the left wing of a pair of crystals that are a mirror regard of all(prenominal) other. It is then recrystallised and the predominance of the l-enantiomorph is found to be change order and the process is repeated until no further change is release and a concentration of 8 grams per 100 cc of aqueous solution is obtained. Finally the product obtained is l-amphetamine d-tartrate. d-amphetamine may be repossess from this by the addition of tartaric acidic for the formation of acid tartrates and separation of d-amphetamine d-bitartrate by crystallisation. Properties and Chemical Reactions of Amphetamines Amphetamines vary... If you want t! o get a full essay, order it on our website: OrderEssay.net

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